C57BL/6JGpt-CD274em3Cd302d12132/Gpt
Pdl1-KO|Strain NO.T009724
Knockout (KO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-CD274em3Cd302d12132/Gpt |
| Strain Number: | T009724 |
| Official Symbol: | Cd274,Pdl1 |
| Strain Strategy: | T009724.Cd274 Cas9-KO Strategy-EN.pdf |
| Official Full Name: | CD274 antigen |
| Also Known As: | A530045L16Rik,B7h1,Pdcd1l1,Pdcd1lg1,Pdl1 |
| NCBI Number: | 60533 |
| MGI Number: | 1926446 |
| Chromosome: | 19 |
| Deletion (size): | -302bp-12132bp |
| Research Areas: | Metabolic research,homeostasis/metabolism,Developmental Biology,mortality/aging,immune system,nervous system,behavior/neurological,Physiological system,integument,skeleton,hematopoietic system,Cell biology,Cell Proliferation,Cell death,cellular,Cell localization,Cytoplasmic vesicle,endosome,Organelles membrane,Molecular biology,Signal Transduction |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Knockout (KO) |
| Genotyping Protocols: | T009724.Cd274 Genotyping Protocol(KO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Suppression of tumor or host intrinsic CMTM6 drives antitumor cytotoxicity in a PD-L1 independent manner2. CMTM6 maintains B cell-intrinsic CD40 expression to regulate anti-tumor immunity |
| Gene Family: | B7 familyC2-set domain containingCD moleculesReceptor ligandsV-set domain containing |