C57BL/6JGpt-CD274em3Cd302d12132/Gpt

Pdl1-KO|Strain NO.T009724

Knockout (KO)

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BASIC INFORMATION
Strain Name: C57BL/6JGpt-CD274em3Cd302d12132/Gpt
Strain Number: T009724
Official Symbol: Cd274,Pdl1
Strain Strategy: T009724.Cd274 Cas9-KO Strategy-EN.pdf
Official Full Name: CD274 antigen
Also Known As: A530045L16Rik,B7h1,Pdcd1l1,Pdcd1lg1,Pdl1
NCBI Number: 60533
MGI Number: 1926446
Chromosome: 19
Deletion (size): -302bp-12132bp
Research Areas: Metabolic research,homeostasis/metabolism,Developmental Biology,mortality/aging,immune system,nervous system,behavior/neurological,Physiological system,integument,skeleton,hematopoietic system,Cell biology,Cell Proliferation,Cell death,cellular,Cell localization,Cytoplasmic vesicle,endosome,Organelles membrane,Molecular biology,Signal Transduction
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Knockout (KO)
Genotyping Protocols: T009724.Cd274 Genotyping Protocol(KO).pdf
Inventory Status: Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. Suppression of tumor or host intrinsic CMTM6 drives antitumor cytotoxicity in a PD-L1 independent manner2. CMTM6 maintains B cell-intrinsic CD40 expression to regulate anti-tumor immunity
Gene Family: B7 familyC2-set domain containingCD moleculesReceptor ligandsV-set domain containing