C57BL/6JGpt-Nlrp3em1Cflox/Gpt
Nlrp3-flox|Strain NO.T010872
Conditional knockout (cKO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Nlrp3em1Cflox/Gpt |
| Strain Number: | T010872 |
| Official Symbol: | Nlrp3 |
| Strain Strategy: | T010872. Nlrp3 Cas9-CKO Strategy-EN.pdf |
| Official Full Name: | NLR family, pyrin domain containing 3 |
| Also Known As: | AGTAVPRL,AII/AVP,Cias1,FCAS,FCU,MWS,Mmig1,NALP3,Pypaf1 |
| NCBI Number: | 216799 |
| MGI Number: | 2653833 |
| Chromosome: | 11 |
| Distance Between Two Loxps: | 4500bp |
| Research Areas: | Metabolic research,adipose tissue,Protein metabolism,homeostasis/metabolism,Developmental Biology,cell differentiation,growth/size/body,mortality/aging,immune system,Inflammation,nervous system,Physiological system,integument,skeleton,reproductive system,digestive/alimentary system,liver/biliary system,renal/urinary system,hematopoietic system,limbs/digits/tail,Cell biology,Cell death,cellular,Cell localization,endoplasmic reticulum,Golgi apparatus,cell nucleus,Molecular biology,Signal Transduction,DNA transcription,DNA binding protein |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | T010872.Nlrp3 Genotyping Protocol(CKO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Microglial NLRP3 inflammasome activates neurotoxic astrocytes in depression-like mice2. Inhibition of the interaction between microglial adenosine 2A receptor and NLRP3 inflammasome attenuates neuroinflammation posttraumatic brain injury |
| Gene Family: | NLR familyPyrin domain containing |