C57BL/6JGpt-Vdrem1Cflox/Gpt

Vdr-flox|Strain NO.T009862

Conditional knockout (cKO)

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BASIC INFORMATION
Strain Name: C57BL/6JGpt-Vdrem1Cflox/Gpt
Strain Number: T009862
Official Symbol: Vdr
Strain Strategy: T009862.Vdr Cas9-CKO Strategy-EN.pdf
Official Full Name: vitamin D (1,25-dihydroxyvitamin D3) receptor
Also Known As: Nr1i1
NCBI Number: 22337
MGI Number: 103076
Chromosome: 15
Distance Between Two Loxps: 1463bp
Research Areas: Metabolic research,homeostasis/metabolism,Lipid Metabolism,Developmental Biology,cell differentiation,growth/size/body,mortality/aging,immune system,nervous system,hearing/ear,behavior/neurological,Physiological system,integument,cardiovascular system,skeleton,craniofacial ,Muscle ,reproductive system,digestive/alimentary system,renal/urinary system,endocrine/exocrine glands,hematopoietic system,limbs/digits/tail,Cell biology,Cell Proliferation,Cell death,cellular,Cell localization,cell nucleus,Organelles membrane,Molecular biology,Signal Transduction,DNA transcription,DNA binding protein,Lipid binding protein
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Conditional knockout (cKO)
Genotyping Protocols: T009862.Vdr Genotyping Protocol(CKO).pdf
Inventory Status: Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. Discovery of vitexin as a novel VDR agonist that mitigates the transition from chronic intestinal inflammation to colorectal cancer
Gene Family: Nuclear hormone receptorsProtein phosphatase 1 regulatory subunits