C57BL/6JGpt-Fgf4em1Cflox/Gpt
Fgf4-flox|Strain NO.T009264
Conditional knockout (cKO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Fgf4em1Cflox/Gpt |
| Strain Number: | T009264 |
| Official Symbol: | Fgf4 |
| Strain Strategy: | T009264.Fgf4 Cas9-CKO Strategy-EN.pdf |
| Official Full Name: | fibroblast growth factor 4 |
| Also Known As: | Fgf-4,Fgfk,HBGF-4,Hst1,Hstf-1,KS3,hst,hst-1,kFGF |
| NCBI Number: | 14175 |
| MGI Number: | 95518 |
| Chromosome: | 7 |
| Distance Between Two Loxps: | 15000bp |
| Research Areas: | Metabolic research,Protein metabolism,Developmental Biology,cell differentiation,embryo,growth/size/body,mortality/aging,nervous system,vision/eye,Physiological system,skeleton,reproductive system,limbs/digits/tail,Cell biology,Cell Proliferation,Cell death,cellular,Molecular biology,Signal Transduction,DNA transcription |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | T009264.Fgf4 Genotyping Protocol(CKO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. FGF4 protects the liver from nonalcoholic fatty liver disease by activating the AMP-activated protein kinase-Caspase 6 signal axis2. A non-mitogenic FGF4 analog alleviates non-alcoholic steatohepatitis through an AMPK-dependent pathway |
| Gene Family: | Fibroblast growth factor familyReceptor ligands |