C57BL/6JGpt-Slc7a11em1Cflox/Gpt
Slc7a11-flox|Strain NO.T015188
Conditional knockout (cKO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Slc7a11em1Cflox/Gpt |
| Strain Number: | T015188 |
| Official Symbol: | Slc7a11 |
| Strain Strategy: | T015188.Slc7a11 Cas9-CKO Strategy-EN.pdf |
| Official Full Name: | solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 |
| Also Known As: | 9930009M05Rik,AI451155,sut,xCT |
| NCBI Number: | 26570 |
| MGI Number: | 1347355 |
| Chromosome: | 3 |
| Distance Between Two Loxps: | 3019bp |
| Research Areas: | Metabolic research,homeostasis/metabolism,Developmental Biology,immune system,Tumor research,nervous system,vision/eye,Physiological system,integument,pigmentation,hematopoietic system,Cell biology,Cell Proliferation,Cell death,Cytoskeleton,cellular,Cell localization,endoplasmic reticulum,Organelles membrane,Molecular biology,Signal Transduction,transporter |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | T015188.Slc7a11 Genotyping Protocol(CKO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Slc7a11 stimulates glutathione synthesis to preserve fatty acid metabolism in primary hepatocytes2. Essentiality of SLC7A11-mediated nonessential amino acids in MASLD |
| Gene Family: | Solute carriers |