C57BL/6JGpt-Anxa1em1Cflox/Gpt
Anxa1-flox|Strain NO.T016067
Conditional knockout (cKO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Anxa1em1Cflox/Gpt |
| Strain Number: | T016067 |
| Official Symbol: | Anxa1 |
| Strain Strategy: | T016067.Anxa1 Cas9-CKO Strategy-EN.pdf |
| Official Full Name: | annexin A1 |
| Also Known As: | Anx-1,Anx-A1,C430014K04Rik,Lpc-1,Lpc1 |
| NCBI Number: | 16952 |
| MGI Number: | 96819 |
| Chromosome: | 19 |
| Distance Between Two Loxps: | 9700bp |
| Research Areas: | Metabolic research,adipose tissue,Protein metabolism,homeostasis/metabolism,Lipid Metabolism,Developmental Biology,cell differentiation,growth/size/body,mortality/aging,immune system,Tumor research,nervous system,synapse,Physiological system,cardiovascular system,skeleton,craniofacial ,digestive/alimentary system,endocrine/exocrine glands,hematopoietic system,Cell biology,Cell Proliferation,Cell death,Cytoskeleton,Mitochondrial research,cellular,Cell localization,Cytoplasmic vesicle,endosome,cell nucleus,cytomembrane,Organelles membrane,Molecular biology,Signal Transduction,DNA binding protein,Regulation of enzyme activity,hydrolytic enzyme,Lipid binding protein,RNA binding protein |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | T016067.Anxa1 Genotyping Protocol(CKO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. VIP Stabilizes the Cytoskeleton of Schlemm’s Canal Endothelia via Reducing Caspase-3 Mediated ZO-1 Endolysosomal Degradation2. Loss of Annexin A1 in macrophages restrains efferocytosis and remodels immune microenvironment in pancreatic cancer by activating the cGAS/STING pathway |
| Gene Family: | AnnexinsReceptor ligands |