C57BL/6JGpt-Myd88em1Cflox/Gpt
Myd88-flox|Strain NO.T009598
Conditional knockout (cKO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
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BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Myd88em1Cflox/Gpt |
| Strain Number: | T009598 |
| Official Symbol: | Myd88 |
| Strain Strategy: | T009598.Myd88 Cas9-CKO Strategy-EN.pdf |
| Official Full Name: | myeloid differentiation primary response gene 88 |
| NCBI Number: | 17874 |
| MGI Number: | 108005 |
| Chromosome: | 9 |
| Distance Between Two Loxps: | 3600bp |
| Research Areas: | Metabolic research,Developmental Biology,immune system,cardiovascular system,Tumor research,nervous system,Signal Transduction,skeleton,vision/eye,hearing/ear,respiratory system,adipose tissue,Cell Proliferation,Cell death,DNA transcription,digestive/alimentary system,Protein metabolism,liver/biliary system,renal/urinary system,Physiological system,endocrine/exocrine glands,homeostasis/metabolism,behavior/neurological,cell differentiation,Cell biology,Molecular biology,cellular,growth/size/body,hematopoietic system,Cell localization,cell nucleus,Organelles membrane,synapse |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | T009598.Myd88 Genotyping Protocol(CKO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Macrophage-specific MyD88 deletion and pharmacological inhibition prevents liver damage in non-alcoholic fatty liver disease via reducing inflammatory response2. Schisandrin B Attenuates Diabetic Cardiomyopathy by Targeting MyD88 and Inhibiting MyD88-Dependent Inflammation |
| Gene Family: | My-T-BRC complexTIR domain containing |