Cell Line Engineering

Gene editing is a genetic engineering technique that enables precise modifications, such as knockouts, insertions, and specific point mutations, to target genes or their transcription products. This is primarily achieved through artificial nucleases, which allow for specific gene sequence knockout, insertion, or precision editing within the genome. The CRISPR-Cas9 system can be used to knock out or overexpress certain genes, making it a valuable tool for screening target genes. When combined with relevant functional assays, it can identify key target genes essential for specific biological processes or diseases.

 

GPT has a refined CRISPR-Cas9 system that offers higher editing efficiency and lower off-target effects. We offer a wide range of gene editing services, including gene knockout, gene knock-in, gene overexpression, and modifications with luciferase, among others. Depending on the unique characteristics of different cells, we choose the most suitable transfection or infection methods, such as lipid transfection, electroporation, or lentiviral infection.

  • CRISPR Gene Editing Cell Lines

  • Luciferase Modified Cell Lines

  • Mouse Derived Cell Lines

  • CDX


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