Evaluation of Anti-tumor Effect of Gut Microbiota

More and more studies have shown that gut microbiota have notable impact on cancer therapy. Therapies such as chemo-therapeutic drugs and immune checkpoint inhibitors can affect the integrity of the intestinal barrier and influence the microbe-host interaction. Gut microbiota interacting with the matrix, nerve, endocrine, immune cells in the intestinal tract can have systemic effects on hosts, and ultimately affect the host's immune response, making gut microbiota essential for anti-tumor efficacy studies. Using severely immunodeficient germ-free NCG mouse models, we established a triple humanized mouse models which have human tumor cells, human immune checkpoint components, and human gut microbiota, allowing for evaluation of the impact of gut microbiota on the anti-tumor efficacy of anti-tumor drugs.


图片1.png

TALK WITH OUR EXPERTS

GemPharmatech is committed to protecting and respecting your privacy, and we'll only use your personal information to administer your account and to provide the products and services you requested from us. From time to time, we would like to contact you about our products and services, as well as other content that may be of interest to you. If you consent to us contacting you for this purpose, please click below to say how you would like us to contact you:

In order to provide you with the content requested, we need to store and process your personal data. If you consent to us storing your personal data for this purpose, please click the checkbox below.

You can unsubscribe from these communications at any time. For more information on how to unsubscribe, our privacy practices, and how we are committed to protecting and respecting your privacy, please review our Privacy Policy.