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Signaling Pathways

Wnt ß-catenin Signaling

This pathway is involved in the regulation of key cellular functions such as stem cell renewal, proliferation, differentiation, migration, and apoptosis. Altered function of this pathway has been associated with cancer and Alzheimer disease.

The pathway below is interactive, meaning you can click on an active pathway component (highlighted in orange) to learn more about available mouse models relevant to that specific gene and pathway function.